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however,within the other hand, Two integral issues remain unsettled so far: (1) The absolute copy number of the threshold level that varied slightly but extremely among the above labs; since (2) The timing of bone marrow sampling during CR best in predicting patient clinical outcome. in relation to the first issue, Many variables of CBFbeta/MYH11 realtime PCR procedure need to be michael kors factory consistent: The European Sanco Concerted Action has devoted many efforts to this task as well as to reduce interlabs variability and to implement highly reproducible assays. further, We agree with Martinelli et al1 that the amount of minimal residual disease (MRD) Observed during CR is critically decided by the timing of bone marrow sampling as well as by the chemotherapy protocol adopted (Ie generic vs high doses of ARAC). louis vuitton outlet In this hookup, We have recently updated our preliminary results3 of quantitative MRD after induction and coalescence in patients treated with standard doses of ARAC: proper induction, 6/7 those with >100 copies of leukemic transcript relapsed compared to the 2/12 with P=0.003): likewise, After relief, 8/11 women with >10 illegal copies vs 2/12 with P=0.006) Relapsed. It could be interesting to see if similar results were found in patients treated with highdose ARAC regimens as in the protocol employed by Martinelli et al;1 within the, Our results suggest that early monitoring of MRD after induction michael kors outlet or amalgamation therapy is michael kors predictive of relapse, Thus allowing timely treatment changes to overpower resistant disease. to summary it, We are convinced available data of realtime PCR of inv(16) Leukemia are by now strongly related to the patients outcome and treatment, Aiding clinicians to implement more tailored very worthwhile approaches.

surface of pageReferences

Martinelli g, Buonamici S, Visani h, metersalagola e, liccaluga r, Isidori A et ing. Molecular monitoring of acute myeloid leukemia related inv(16): Threshold of CBF/MYH11 transcript copy number above which relapse occurs and below which continuous CR is likely. leukemia 2003; 17: 650 document Buonamici S, Ottaviani o, michael kors discount Testoandi s, Montefusco V, Visani michael kors handbags gary, Bonifazi F et 's. Realtime quantitation of minimal left over disease in inv(16)optimistic people acute michael kors wholesale myeloid leukemia m

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عرض البوم صور Hiencecerry   رد مع اقتباس
قديم 07-18-2013   المشاركة رقم: 34
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الرتبة:

البيانات
التسجيل: Aug 2012
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المشاركات: 2,929 [+]
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الإتصالات
الحالة:
حمود عبيدالله العجوين غير متواجد حالياً
وسائل الإتصال:

كاتب الموضوع : عبيد العجوين المنتدى : منتدى شهيد الواجب/ عبدالله سعد سعود قبلان العجوين
افتراضي رد: يوتيوب لشهيد الواجب عبدالله سعد الرشيدي

رحمه الله واسكنه فسيح جناته












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